Not only its amount but additionally the practical properties of Hb impact effectiveness. This can be illustrated with the observation that an increased Hb-O2 affinity favors O2 loading inside the lung and survival in an hypoxic surroundings (Eaton et al., 1974; Hebbel et al., 1978), While a reduced Hb-O2 affinity favors the discharge of O2 with th
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